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Pulmonary sarcoidosis associated with psoriasis vulgaris: coincidental occurrence or causal association? Case report

2006; BioMed Central; Volume: 6; Issue: 1 Linguagem: Inglês

10.1186/1471-2466-6-26

1471-2466

Melita Nikolopoulou, Stamatis Katsenos, Kostas Psathakis, Εfstathios Rallis, Dimitrios Sampaziotis, P. Panagou, Kostas Tsintiris, Demosthenes Bouros,

Drug-Induced Adverse Reactions

Abstract Background Sarcoidosis is rarely associated with a distinct disease. One disease infrequently associated with sarcoidosis is psoriasis. Case presentation This case study describes a 38-year-old male, who presented with chest pain, high-grade fever, arthralgias and a skin rash accompanied by bilateral hilar lymphadenopathy on his chest radiograph. Extensive investigations including fiber-optic bronchoscopy with bronchoalveolar lavage and labial and skin biopsies, demonstrated that two distinct clinical entities co-existed in the same patient: pulmonary sarcoidosis and psoriasis vulgaris. Combination therapy for both diseases was applied and the patient was greatly improved. Conclusion This is the first well-documented case of sarcoidosis and psoriasis in the same patient, reported on the basis of safe and widely-used techniques that were not available until fairly recently. These disorders might share common pathogenic mechanisms that could explain their co-existence in the patient.