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Nuclear morphology of cells in human amniotic fluid in relation to sex of infant

1956; Elsevier BV; Volume: 71; Issue: 4 Linguagem: Inglês

10.1016/0002-9378(56)90579-8

1097-6868

Landrum B. Shettles,

Congenital limb and hand anomalies

Smears were prepared from the cells in amniotic fluid at delivery of 40 patients, 20 of whom had normal female and 20 normal male infants, and stained with a modified Feulgen technique. Many of the nuclei of the intermitotic cells from all of the fluids in which female infants developed contained the characteristic sex chromatin mass; i was not observed in any of the nuclei of cells from amniotic fluids associated with male offspring.