Phenylthiocarbamide taste sensitivity revisited: Complete sorting test supports residual family resemblance
1989; Wiley; Volume: 6; Issue: 3 Linguagem: Inglês
10.1002/gepi.1370060304
ISSN1098-2272
AutoresB. M. Reddy, D. C. Rao, Jean W. MacCluer,
Tópico(s)RNA regulation and disease
ResumoAbstract Phenylthiocarbamide (PTC) taste thresholds were determined in 100 nuclear families using the complete sorting test. Segregation analysis using the mixed model suggested that the variability in PTC thresholds is controlled by a major locus with incomplete dominance as well as by a multifactorial component with significant residual heritability. Such a model explained nearly 96% of the variance, leaving only 4% of the variance in thresholds arising from measurement error and other environmental factors.
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