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A COMPARISON OF THE PLASMA IRON, IRON-BINDING CAPACITY, STERNAL MARROW IRON AND OTHER METHODS IN THE CLINICAL EVALUATION OF IRON STORES

1958; American College of Physicians; Volume: 48; Issue: 1 Linguagem: Inglês

10.7326/0003-4819-48-1-60

1539-3704

Ernest Beutler, M Robson, E BUTTENWIESER,

Hemoglobinopathies and Related Disorders

Article1 January 1958A COMPARISON OF THE PLASMA IRON, IRON-BINDING CAPACITY, STERNAL MARROW IRON AND OTHER METHODS IN THE CLINICAL EVALUATION OF IRON STORESE. BEUTLER, M.D., M. J. ROBSON, B.S., E. BUTTENWIESER, B.S.E. BEUTLER, M.D., M. J. ROBSON, B.S., E. BUTTENWIESER, B.S.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-1-60 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCorrect evaluation of the iron stores helps the clinician to distinguish the anemia of iron deficiency from that of chronic infection, renal disease and cancer. It makes possible a presumptive diagnosis of hemochromatosis. We have recently reviewed methods of evaluating the iron stores.1 Several of these appear to have considerable merit, and it is unfortunate that they have been neglected by most physicians.The most direct method of assessing the iron stores is the examination of fragments of sternal bone marrow for stainable iron. Although on occasion this method may give misleading results, it has been found to be highly...Bibliography1. Beutler E: The clinical evaluation of iron stores, New England J. Med. 256: 692-697, 1957. CrossrefMedlineGoogle Scholar2. RathFinch CECA: Sternal marrow hemosiderin, J. Lab. and Clin. Med. 33: 81-86, 1948. MedlineGoogle Scholar3. DavidsonJennison WMRF: The relationship between iron storage and anaemia, J. Clin. Path. 5: 281-285, 1952. CrossrefMedlineGoogle Scholar4. Hutchison HE: The significance of stainable iron in sternal marrow sections, Blood 8: 236-248, 1953. CrossrefMedlineGoogle Scholar5. 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Jasinski B: Zur Frage der nicht- und der leicht anamischen Eisenmangelkrankheit, Praxis 38: 811-816, 1950. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication April 3, 1957.From the Argonne Cancer Research Hospital, USAEC, and the Department of Medicine, The University of Chicago, Chicago, Illinois.Requests for reprints should be addressed to Ernest Beutler, M.D., 950 East Fifty-ninth Street, Chicago 37, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited BySerum or plasma ferritin concentration as an index of iron deficiency and overloadAre Current Serum and Plasma Ferritin Cut-offs for Iron Deficiency and Overload Accurate and Reflecting Iron Status? 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Iron StoresUsing a Clinical Laboratory in the Diagnosis of AnemiaIron Absorption in Relation to Transferrin Saturation and Other FactorsDepoteisen im KnochenmarkStudies on GlycoproteinsStudies on the serum iron-binding capacityIron metabolism in rheumatoid arthritisThe Anemia of Lymphomas and LeukemiasMACROCYTIC, NON-MEGALOBLASTIC, FOLIC-ACID-RESPONSIVE ANAEMIAS OF CHILDHOODMarrow Iron An Evaluation of Depleted Stores in a Series of 1,332 Needle BiopsiesL. D. ELLIS, M.D., W. N. JENSEN, M.D., F.A.C.P., M. P. WESTERMAN, M.D.The Use of Ferrokinetics in the Evaluation of Busulphan Therapy in Polycythaemia VeraComparison of Hemosiderin Estimation in Bone Marrow Sections and Bone Marrow SmearsErgebnisse eines Tests zum Nachweis vermehrter Eisenspeicherung im Organismus bei LeberkrankheitenIron metabolism in premature infantsPatterns of anemia in chronic myelocytic leukemiaThe structural and functional status of the liver in tropical sprueIntriguing Types of Hypochromic AnemiaIron storage in human disease: Fractionation of hepatic and splenic iron into ferritin and haemosiderin with histochemical correlationsClinical Use of the Arm Counter in Blood Clearance StudiesRelative Effectiveness of Ferroglycine Sulfate and Ferrous SulfateUse of the Prussian Blue Reaction in the Differential Diagnosis of AnemiasWARREN D. BOWMAN JR., M.D.Further Studies on the Interrelationship between Hemosiderin and Sideroblasts in Bone Marrow SmearsIRON THERAPY IN CHRONICALLY FATIGUED, NONANEMIC WOMEN: A DOUBLE-BLIND STUDY*E. BEUTLER, M.D., S. E. LARSH, M.D., C. W. GURNEY, M.D.Die idiopathische LungenhämosideroseProgress in biochemical investigations: 1958Studies on Iron Absorption Following Partial GastrectomyDer Eisentransport im Blut nach peroraler, intraven�ser und intramuskul�rer EisenzufuhrTHE RED CELL INDICES IN THE DIAGNOSIS OF IRON-DEFICIENCY ANEMIA*ERNEST BEUTLER, M.D.Hemosiderin Estimations and Sideroblast Counts in the Differential Diagnosis of Iron Deficiency and other AnemiasREFERENCES 1 January 1958Volume 48, Issue 1Page: 60-82KeywordsAnemiaBlood plasmaBone marrowHemochromatosisHemoglobinHospital medicineIron deficiencyIron deficiency anemiaRenal cancerRenal diseases Issue Published: 1 January 1958 PDF DownloadLoading ...