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Artigo Revisado por pares
BIBTEX RIS

Anti-asthmatic effects of onions

1988; Elsevier BV; Volume: 37; Issue: 23 Linguagem: Inglês

10.1016/0006-2952(88)90663-6

ISSN

1873-2968

Autores

Walter Dorsch, Hildebert Wagner, Thomas Bayer, Beate Fessler, Guido Hein, Johannes Ring, Peter Scheftner, Werner Sieber, Th. Strasser, Eva‐Christine Weiss,

Tópico(s)

Urticaria and Related Conditions

Resumo

Five alk(en)ylsulfinothioic acid alk(en)yl-esters isolated from onions and four synthetic thiosulfinates inhibited 5-lipoxygenase of porcine leucocytes, histamine release and leukotriene B4 and C4 biosynthesis of human polymorphonuclear leucocytes, thromboxane B2 biosynthesis by human platelets and allergen- and PAF-induced bronchial obstruction of guinea-pigs. The anti-asthmatic and anti-inflammatory effects of onions depend in part on the thiosulfinate moiety: (Formula: see text).

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