Platelet aggregation induced by latex particles
1989; Elsevier BV; Volume: 10; Issue: 4 Linguagem: Inglês
10.1016/0142-9612(89)90101-4
ISSN1878-5905
AutoresMasaki Miyamoto, Shigeru Sasakawa, Tatsushi Ozawa, Haruma Kawaguchi, Yasuji Ohtsuka,
Tópico(s)Proteins in Food Systems
ResumoLatex particles induced platelet aggregation associated with the release of ATP from the platelets. The smaller the diameter of particles having the same surface structure, the greater numbers or greater total surface area of particles were required for both reactions. The higher Hydrophobie and higher negatively charged particles, having a diameter of about 0.3 urn, induced platelet aggregation most easily. Hydrophilic particles without high negative surface potential activated platelets only a little. Particle-induced platelet aggregation is not only caused by colloidal electronic force and hydrophobic interaction between platelets and latex particles but also by factors concerning cell activation.
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