Crystalline constituents of euphorbiaceae—V
1966; Elsevier BV; Volume: 22; Issue: 8 Linguagem: Inglês
10.1016/s0040-4020(01)99083-0
ISSN1464-5416
AutoresL. Ramachandra Row, C. Srinivasulu, Mark E. Smith, G.S.R.Subba Rao,
Tópico(s)Phytochemistry and biological activity of medicinal plants
ResumoAn improved method for the isolation of phyllanthin and hypophyllanthin from the leaves of Phyllanthus niruri Linn. has been described. Their molecular formulae have been revised as C24H34O6 and C24H30O7. The structure of phyllanthin is now shown to be (+)3,4,3′,4′,9,9′-hexamethoxy-8:8′-butyrolignan (IV) from its reactions and degradation to veratric acid. NMR spectra of phyllanthin and its derivatives support this structure.
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