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Recent advances in the treatment of neurodegenerative disorders and cognitive dysfunction

1995; Elsevier BV; Volume: 26; Issue: 6 Linguagem: Inglês

10.1016/0306-3623(95)90079-9

1879-0011

Giorgio Racagni, N. Brunello, S.Z. Langer,

Cholinesterase and Neurodegenerative Diseases

Classification, epidemiology and early diagnosis of age-related cognitive impairment - a continuum from age-related changes to diseases? brain imaging single photon emission computed tomography during cognitive stimulation - potential interest in the diagnosis of Alzheimer's EEG/EP mapping in neurodegenerative and cognitive disorders a digital-video medical record system for assessing demented patients neuroimaging in dementia with white matter changes molecular genetics of neurodegenerative disorders - Alzheimer's disease cholinomimetic therapy of Alzheimer's disease - does it slow deterioration? nicotinic agonists in Alzheimer's disease - does the molecular diversity of nicotine receptors offer the opportunity for developing CNS-selective cholinergic channel activators? effects of neuropeptides on learning and memory facilitation of recovery after brain damage by ACTH peptides serotonergic mechanisms in age-related cognitive impairment and in dementias 5-HT[3] antagonists and disorders of cognition (3)H-imipramine binding and peripheral-type benzodiazepine receptors in Parkinson's disease - relationship with depression and anxiety molecular mechanisms of excitotoxicity brain nitric oxide synthesis and neurodegeneration mechanisms and role of oxygen free radicals on CNS pathology role of nitric oxide in the pathophysiology of neurodegeneration induced by tacrine in lithium pretreated rats convergent inhibition of glutamate uptake by arachidonic acid and oxygen free radicals - molecular mechanisms and relevance to neurodegenerative pathologies molecular basis of antioxidant therapy antioxidant therapy and neuroprotection mechanisms of long-term potentiation in cultured hippocampal neurons - identification of a presynaptic event which might support the enhanced glutamate release pharmacology of excitatory amino acid receptors neurotransmission in aging - therapeutic aspects primate models of cognitive dysfunction in neurodegenerative disorders neuroendocrine factors in neurodegenerative and cognitive disorders studying the rate of decline in Alzheimer's disease - implications for therapeutic trials a possible relationship between the plaques and tangles of Alzheimer's disease neurotrophic factors - possibilities and limitations in the treatment of neurodegenerative disorders regulation of basic fibroblast growth factor gene expression in rat brain following limbic motor seizures neural transplantation in Parkinson's disease - strategies for improved graft survival and efficacy modulatory influences on astroglial reaction induced by brain lesions a radical basis nigrostriatal dopamine cell death in Parkinson's disease oxygen free radicals and Parkinson's disease Trophic-Like actions of (-)-deprenyl on neurons and astroglia the efficacy and safety of piracetam in the rehabilitation of stroke patients.