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Iron-Chelating Therapy and the Treatment of Thalassemia

1997; Elsevier BV; Volume: 89; Issue: 3 Linguagem: Inglês

10.1182/blood.v89.3.739

1528-0020

Nancy F. Olivieri, Gary M. Brittenham,

Neonatal Health and Biochemistry

THE LAST 3 decades have witnessed profound changes in the management of patients with thalassemia major. Regular red blood cell (RBC) transfusions eliminate the complications of anemia and compensatory bone marrow (BM) expansion, permit normal development throughout childhood, and extend survival.[1