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Agar-Gel Precipitin-Inhibition Test for Coccidioidomycosis

1967; American Society for Microbiology; Volume: 15; Issue: 5 Linguagem: Inglês

10.1128/am.15.5.1054-1061.1967

0003-6919

John G. Ray, John L. Converse,

Peptidase Inhibition and Analysis

In this study of saprophytic and parasitic growth-phase extracts of Coccidioides immitis , an antigen from the spherule culture supernatant fluid detected a specific antibody in heretofore serologically negative suspect coccidioidomycosis human sera when diffused in agar-gel. This antigen-antibody reaction occurred also in some of the serologically positive human coccidioidomycosis sera. This study indicates that this antigen-antibody reaction should be utilized as a possible routine serological test for complete serodiagnosis.