Integrated Whole Transcriptome and DNA Methylation Analysis Identifies Gene Networks Specific to Late-Onset Alzheimer's Disease
2015; IOS Press; Volume: 44; Issue: 3 Linguagem: Inglês
10.3233/jad-141989
ISSN1875-8908
AutoresCrystal Humphries, Martin Kohli, Lubov Nathanson, Patrice L. Whitehead, Gary W. Beecham, Eden R. Martin, Deborah C. Mash, Margaret A. Pericak‐Vance, John R. Gilbert,
Tópico(s)Peroxisome Proliferator-Activated Receptors
ResumoPrevious transcriptome studies observed disrupted cellular processes in late-onset Alzheimer's disease (LOAD), yet it is unclear whether these changes are specific to LOAD, or are common to general neurodegeneration. In this study, we address this qu
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