Artigo Acesso aberto Revisado por pares

Integrated Whole Transcriptome and DNA Methylation Analysis Identifies Gene Networks Specific to Late-Onset Alzheimer's Disease

2015; IOS Press; Volume: 44; Issue: 3 Linguagem: Inglês

10.3233/jad-141989

ISSN

1875-8908

Autores

Crystal Humphries, Martin Kohli, Lubov Nathanson, Patrice L. Whitehead, Gary W. Beecham, Eden R. Martin, Deborah C. Mash, Margaret A. Pericak‐Vance, John R. Gilbert,

Tópico(s)

Peroxisome Proliferator-Activated Receptors

Resumo

Previous transcriptome studies observed disrupted cellular processes in late-onset Alzheimer's disease (LOAD), yet it is unclear whether these changes are specific to LOAD, or are common to general neurodegeneration. In this study, we address this qu

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