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Rapid Qualitative TSH Test to Screen for Primary Hypothyroidism

1997; American Association for Clinical Chemistry; Volume: 43; Issue: 6 Linguagem: Inglês

10.1093/clinchem/43.6.1097a

1530-8561

Jerome M. Hershman, L. Van de Berg,

Erythrocyte Function and Pathophysiology

We evaluated a qualitative, solid-phase two-site immunochromatographic assay (ThyroChek; Franklin Diagnostics, Cedar Knolls, NJ) for identifying serum samples that contain thyrotropin (TSH) in a concentration >5 mU/L. The test is intended for use as a screening method for primary hypothyroidism. Reagents were provided to us by the manufacturer. The test is performed by adding 4 drops of serum (∼0.1 mL) to the well of the cassette. The serum is adsorbed onto the nitrocellulose membrane, exposed to the mobile-phase antibody to …