1,5-Dicarbonyl compounds
1986; Elsevier BV; Volume: 42; Issue: 17 Linguagem: Inglês
10.1016/s0040-4020(01)82058-5
ISSN1464-5416
AutoresPierre Duhamel, Laurent Hennequin, J.‐M. POIRIER, G. TAVEL, C. VOTTERO,
Tópico(s)Phosphorus compounds and reactions
ResumoIn this report, a general method for the preparation of 1,5-dicarbonyl compounds and six membered ring annelation is described. This method involves the reaction of hemiacetal vinylogs 1 with enol ethers 2 or 3 in the presence of a Lewis acid. This reaction was successfully applied to the enol ethers of α and α,α'-hindered ketones such as 2,2,6-trimethyl cyclohexanone. α-Cyperone and 6-epi-α-cyperone were obtained using this process.
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