Identification of radiolabeled metabolites of nicotine in rat bile
1993; Elsevier BV; Volume: 621; Issue: 1 Linguagem: Inglês
10.1016/0378-4347(93)80075-f
ISSN1872-812X
AutoresMark J. Seaton, Elliot S. Vesell, Haoming Luo, E. M. Hawes,
Tópico(s)Nicotinic Acetylcholine Receptors Study
ResumoFour metabolites of nicotine, including two glucuronides, have been separated by high-performance liquid chromatography. This separation was applied to identification of biliary metabolites of radiolabeled nicotine by radiometric detection. S-(−)-Nicotine N-glucuronide was synthesized and used as a standard in method development.
Referência(s)