32-O-03-Study of the reaction of a Ca-clinoptilolite and human bile
2001; Elsevier BV; Linguagem: Inglês
10.1016/s0167-2991(01)81306-9
ISSN2542-6613
AutoresR. Simón Carballo, G. Rodrı́guez-Fuentes, Cevallos Urbina, Alex Coene Fleitas,
Tópico(s)Metabolism and Genetic Disorders
ResumoThis chapter discusses the study of the reaction of calcium (Ca)-clinoptilolite and human bile. The Ca exchanged form of the purified natural clinoptilolite (NZ) from the Tasajeras deposit, Cuba, is the active ingredient of a drug designed to reduce total blood cholesterol and prevent atherosclerosis. The study of the Ca2+-NZ-human bile reaction reveals that it occurs through the adsorption of three major human bile compounds—namely, bile acids, phospholipids, and bilirubin. The adsorption of phospholipids on the external surface of the clinoptilolite crystals produce a phospholipids–zeolite interface with anionic activity that allows the adsorption of bile acids.
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