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Abstract 9769: Measurement of Myocardial Necrosis Biomarkers After Surgical or Percutaneous Intervention Assessed by Cardiac Magnetic Resonance for Diagnosis of Procedure-Related Myocardial Infarction. The MASS-5 Trial

2014; Lippincott Williams & Wilkins; Volume: 130; Linguagem: Inglês

ISSN

1524-4539

Autores

Whady Hueb, Paulo Cury Rezende, Leandro Menezes Alves da Costa, Rodrigo M Vieira de Melo, Fernando T Oikawa, César Higa Nomura, Alexandre Volney Villa, Célia Maria Cássaro Strunz, Alexandre Ciappina Hueb, Expedito E Silva, José Antônio Franchini Ramires, Roberto Kalil Filho,

Tópico(s)

Cardiac Imaging and Diagnostics

Resumo

Introduction: The correlation between the elevation of cardiac biomarkers and diagnosis of procedure-related myocardial infarction (MI) continues to be debated, especially since the emergence of high-sensitive troponin assays (cTnI). However, late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR) has been established as an alternative for diagnosing AMI. Methods: We prospectively studied 219 patients with stable multivessel coronary artery disease and preserved ventricular function formally indicated for percutaneous or surgical revascularization. Measurements of biomarkers like high-sensitive troponin I (cTnI) and creatine kinase (CKMB) were systematically obtained before and after the procedure, 6, 12, 24, and 36 hours after PCI and up to 72 hours after CABG. Furthermore, CMR was performed in all patients before and after the procedures. The diagnosis of MI was defined as up to 5 times and 10 times the 99th percentile, for PCI and CABG, respectively. Results: Of 219 patients included in t...

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