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THE BIOLOGY OF METACORTICOID HYPERTENSION

1958; American College of Physicians; Volume: 49; Issue: 6 Linguagem: Inglês

10.7326/0003-4819-49-6-1281

1539-3704

F. M. Sturtevant,

Hormonal Regulation and Hypertension

Article1 December 1958THE BIOLOGY OF METACORTICOID HYPERTENSIONF. M. STURTEVANT, Ph.D.F. M. STURTEVANT, Ph.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-6-1281 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe search for methods of treatment of human essential hypertension over the last half-century has led to the laboratory exploration of several dozen experimental counterparts. Most studies have been concerned with four major types of experimental hypertension: neurogenic, renal, renoprival and hormonal. In 1953 and 1954, Green1-4reviewed the similarities and differences among human and experimental hypertensions and concluded that "essential hypertension is simulated most closely, in both its physiologic and anatomic characteristics, by the post-DCA (metacorticoid) syndrome."1The purpose of the present report is to collect and review all of the available information on this syndrome that has appeared...Bibliography1. Green DM: Experimental hypertension, Ann. Int. Med. 39: 333, 1953. LinkGoogle Scholar2. Green DM: The changing patterns of sodium metabolism in hypertension, in Proceedings of the Second Annual Meeting, Council for High Blood Pressure Research, American Heart Association, 1953, International Press, New York, p. 64. Google Scholar3. Green DM: Experimental hypertension and clinical practice, Am. Pract. and Digest Treat. 5: 243, 1954. MedlineGoogle Scholar4. Green DM: Hypertension, in Third Annual Report on Stress, by H. Selye and A. 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GomezHooblerBlaquier ASWP: Effect of renal transplant in adrenocortical hypertension, The Physiologist 1: 28, 1958. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Received for publication July 7, 1958.From the Division of Biological Research, G. D. Searle & Co., Chicago, Illinois.Present address: Smith, Kline & French Laboratories, Philadelphia 1, Pennsylvania.Presented at the University of Michigan Medical School, February 26, 1958.Requests for reprints should be addressed to Miss Barbara Stolley, G. D. Searle & Co., Box 5110, Chicago 80, Illinois. 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