Soluble CD40 ligand and platelets: self-perpetuating pathogenic loop in thrombosis and inflammation?**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

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Soluble CD40 ligand and platelets: self-perpetuating pathogenic loop in thrombosis and inflammation?**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.

2004; Elsevier BV; Volume: 43; Issue: 12 Linguagem: Inglês

10.1016/j.jacc.2004.03.023

ISSN

1558-3597

Autores

Pål Aukrust, Jan Kristian Damås, Nils Olav Solum,

Tópico(s)

Antiplatelet Therapy and Cardiovascular Diseases

Resumo

Platelet adhesion and aggregation at the site of plaque rupture is a crucial event in thrombus formation and the development of acute coronary syndrome (ACS). However, recent studies suggest that platelets also may trigger ACS through other mechanisms such as the stimulation of an inflammatory

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Soluble CD40 ligand and platelets: self-perpetuating pathogenic loop in thrombosis and inflammation?**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology.