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BIBTEX RIS

Lymphokine-activated killer cells are generated before classical cytotoxic T lymphocytes after bone marrow transplantation in mice.

1985; American Association of Immunologists; Volume: 135; Issue: 3 Linguagem: Inglês

10.4049/jimmunol.135.3.1702

ISSN

1550-6606

Autores

V J Merluzzi, Douglas M. Savage, Mark D. Smith, K Last-Barney, Roland Mertelsmann, M A Moore, Karl Welte,

Tópico(s)

Chemokine receptors and signaling

Resumo

Lymphokine-activated killer (LAK) cells are demonstrable within 2 wk after syngeneic or allogeneic (H-2-compatible) bone marrow transplantation in mice. Classical cytotoxic T lymphocytes (CTL) are not active until at least 4 wk after transplant. Both LAK cells and CTL bear the Thy-1 marker and do not possess the murine natural killer cell marker asialo GM.

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