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Biologic properties of eugenol and zinc oxide-eugenol

1992; Elsevier BV; Volume: 73; Issue: 6 Linguagem: Inglês

10.1016/0030-4220(92)90020-q

1878-2175

Kenneth Markowitz, Michael R Moynihan, Mintsai Liu, Syngcuk Kim,

Dental Anxiety and Anesthesia Techniques

Eugenol-containing dental materials are frequently used in clinical dentistry. When zinc oxide-eugenol (ZOE) is applied to a dentinal cavity, small quantities of eugenol diffuse through the dentin to the pulp. Low concentrations of eugenol exert anti-inflammatory and local anesthetic effects on the dental pulp. Thus use of ZOE temporary filling may facilitate pulpal healing; on the other hand, high eugenol concentrations are cytotoxic. Direct application of eugenol to pulp tissue may result in extensive tissue damage. The ability of ZOE-based endodontic sealers to influence periapical tissue healing is considered in view of eugenol's anti-inflammatory and toxic properties.