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Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus.

1992; Elsevier BV; Volume: 267; Issue: 1 Linguagem: Inglês

10.1016/s0021-9258(18)48487-6

1083-351X

Megan Chen, Rebecca T. Suttmann, Joseph C. Wu, Ernest J. Prisbe,

Biochemical and Molecular Research

dideoxynucleoside analogs; ddA, 2',3'-dideoxyadenosine; ddI, 2',3'-dideoxyinosine; ddC, 2'3'-dideoxycytidine; d4C, 2',3'-didehydro-2',3'-dideoxycytidine; AZT, 3'-azido-3'-deoxythymidine; d4T, 2',3'-didehydro-3'-dideoxythymidine; Carbovir, the carbocyclic analog of 2',3'-didehydro-2',3'-dideoxyguanosine; ADRT,