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RECENT DEVELOPMENTS IN THE LABORATORY DIAGNOSIS OF SYPHILIS

1959; American College of Physicians; Volume: 51; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-51-4-748

1539-3704

E GARSON,

Syphilis Diagnosis and Treatment

Article1 October 1959RECENT DEVELOPMENTS IN THE LABORATORY DIAGNOSIS OF SYPHILISWARFIELD GARSON, M.D., M.P.H., F.A.C.P.M.WARFIELD GARSON, M.D., M.P.H., F.A.C.P.M.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-51-4-748 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFrom 1947 to 1955, one of the most unusual and precipitous declines in the reported morbidity of a chronic, social, communicable disease ever observed in the history of our country was recorded. This disease was syphilis. As can be noted in table 1, there was roughly a 68% decline in reported cases of syphilis during these years. The rates for this disease declined over 71%, while cases of infectious syphilis declined approximately 94% during the same time. Observe further that since 1955 there appears to be a leveling off or plateau of reported cases. This leveling off of total syphilis...Bibliography1. LandsteinerMullerPotzl KRO: Zur Frage der Komplementbindungsreaktion bei Syphilis, Wien. klin. Wchnschr. 20: 1565, 1907; Berl. klin. Wchnschr. 45: 86, 1908. Google Scholar2. Eagle H: On the specificity of serologic tests for syphilis as determined by 40,545 tests in a college student population, Am. J. Syph., Gonor. and Ven. Dis. 25: 7, 1941. Google Scholar3. KragLonberg PA: The occurrence of strong unspecific Wassermann-Kahn reaction, Acta dermat.-venereol. 19: 612, 1938. Google Scholar4. Garson W: The treponemal tests for syphilis, South. M. J. 50: 911 (July) 1957. CrossrefMedlineGoogle Scholar5. NelsonMayer RAMM: Immobilization of Treponema pallidum in vitro by antibody produced in syphilitic infection, J. Exper. Med. 89: 369, 1949. CrossrefMedlineGoogle Scholar6. RosenauKent BJJF: Resistance of specifically-sensitized Treponema pallidum to methylene blue stain, Proc. Soc. Exper. Biol. and Med. 91: 579, 1956. 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Health Rep. 72: 761, 1957. CrossrefMedlineGoogle Scholar26. SchmidtBentzon HMW: Investigations on the rapid plasma reagin test, Bull. World Health Org. 19: 563, 1958. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chapel Hill, North Carolina*Received for publication May 16, 1959.Presented before the Fortieth Annual Session of the American College of Physicians, Chicago, Illinois, April 21, 1959.From the Venereal Disease Experimental Laboratory, Venereal Disease Branch, Communicable Disease Center, U. S. Public Health Service, and the Department of Experimental Medicine, School of Public Health, University of North Carolina, Chapel Hill, North Carolina.Requests for reprints should be addressed to Warfield Garson, M.D., Research Professor and Head of the Department of Experimental Medicine School of Public Health, University of North Carolina, Chapel Hill, North Carolina. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTrends in the Diagnosis and Treatment of Syphilis 1 October 1959Volume 51, Issue 4Page: 748-758KeywordsAntigensBiologicsInfectious diseasesProteinsRapid plasma reaginResearch laboratoriesRisk managementSexually transmitted diseasesSyphilisTreponema pallidum ePublished: 1 December 2008 Issue Published: 1 October 1959 PDF downloadLoading ...