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Lymphoproliferation in captive wild ruminants affected with malignant catarrhal fever: 25 cases (1977-1985)

1990; American Veterinary Medical Association; Volume: 196; Issue: 7 Linguagem: Inglês

10.2460/javma.1990.196.07.1141

1943-569X

JeanM. Blake, Niels O. Nielsen, W. P. Heuschele,

Animal Disease Management and Epidemiology

Summary The severity of lymphoproliferative disease associated with malignant catarrhal fever was extremely variable among 25 animals at the San Diego Wild Animal Park. Severe lymphoproliferative disease was seen in 3 of 10 Formosan Sika deer ( Cervus nippon taiouanus ), 3 of 6 Indian Axis deer ( Cervus a axis ), 3 of 6 Barasingha deer ( Cervus d duvauceli ), and 1 of 3 Nilgai ( Boselaphus tragocamelus ). Two Sika deer and 2 Barasingha deer had lesions morphologically indistinguishable from lymphosarcoma. Our findings were consistent with the hypothesis that alcelaphine herpesvirus-1 has oncogenic potential.