Biology of Circulating mRNA
2006; Wiley; Volume: 1075; Issue: 1 Linguagem: Inglês
10.1196/annals.1368.005
ISSN1749-6632
Autores Tópico(s)Renal and related cancers
ResumoA few years after the first description of free-circulating DNA in plasma and serum, the detection of tumor-associated overexpressed mRNA in plasma was also reported. This observation has been confirmed and it seems to be clear that the presence of free-circulating RNA is a ubiquitous phenomenon. In this short review I will discuss some basic aspects of the release mechanisms for the RNA, its biological meaning, and clinical value.
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