THE PARENTERAL USE OF SODIUM LACTATE SOLUTION IN THE PREVENTION OF RENAL COMPLICATIONS FROM PARENTERALLY ADMINISTERED SODIUM SULFADIAZINE
1944; American College of Physicians; Volume: 20; Issue: 4 Linguagem: Inglês
10.7326/0003-4819-20-4-604
ISSN1539-3704
AutoresD. Rourke Gilligan, James A. Dingwall, Walsh McDermott,
Tópico(s)Neonatal Health and Biochemistry
ResumoArticle1 April 1944THE PARENTERAL USE OF SODIUM LACTATE SOLUTION IN THE PREVENTION OF RENAL COMPLICATIONS FROM PARENTERALLY ADMINISTERED SODIUM SULFADIAZINED. ROURKE GILLIGAN, JAMES A. DINGWALL 3D, WALSH MCDERMOTTD. ROURKE GILLIGANSearch for more papers by this author, JAMES A. DINGWALL 3DSearch for more papers by this author, WALSH MCDERMOTTSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-20-4-604 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent studies in this hospital1 and in other clinics2 have demonstrated the effectiveness of adjuvant alkali therapy in preventing renal complications from sulfadiazine. This protective action is attributable to the fact that alkalinization of the urine increases the solubility of sulfadiazine and its N4-acetyl derivative1, 3, 4 and thereby prevents their precipitation in the kidneys and urinary tract.The optimal dosage and mode of administration of alkali during oral therapy with sulfadiazine have been studied in a large series of patients.1Alkalinization of the urine during parenteral therapy with sodium sulfadiazine presents a special problem which is the subject of...Bibliography1. GILLIGANGARBWHEELERPLUMMER DRSCN: Adjuvant alkali therapy in the prevention of renal complications from sulfadiazine, Jr. Am. Med. Assoc., 1943, cxxii, 1160. CrossrefGoogle Scholar2. FOXJENSENMUDGE CLOJGH: The prevention of renal obstruction during sulfadiazine therapy, Jr. Am. Med. Assoc., 1943, cxxi, 1147. CrossrefGoogle Scholar3. 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SCHWARTZFLIPPINREINHOLDDOMM LHFJGAH: The effect of alkali on crystalluria from sulfathiazole and sulfadiazine, Jr. Am. Med. Assoc., 1941, cxvii, 514. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication January 26, 1944.With the technical assistance of Edith M. Beck and Mary A. Cooper.From the Departments of Medicine and Surgery, Cornell University Medical College, and The New York Hospital, New York.†Eleven hundred c.c. were chosen since the contents of the infusion bottles of the prepared solutions used were 550 c.c. each. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byACUTE SUPPURATIVE BRONCHITIS AND BRONCHIOLITIS IN CHRONIC PULMONARY DISEASE: DIAGNOSIS AND MANAGEMENT*LEONARD CARDON, M.D., F.A.C.P., LOUIS LEMBERG, M.D., REGINA S. GREENEBAUM, M.D.Subcutaneous administration of sodium sulfadiazineThe Present Status of Sulfonamide TherapyThe Treatment of Renal Obstruction Resulting Fromsulfadiazine and Sulfamerazine 1 April 1944Volume 20, Issue 4Page: 604-618KeywordsHospital medicineKidneysLactatesResearch designSodiumSurgeryUrine ePublished: 1 December 2008 Issue Published: 1 April 1944 PDF downloadLoading ...
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