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POSITRON EMISSION TOMOGRAPHY FEATURES OF CANINE NECROTIZING MENINGOENCEPHALITIS

2008; Wiley; Volume: 49; Issue: 6 Linguagem: Inglês

10.1111/j.1740-8261.2008.00437.x

1740-8261

Kidong Eom, CHAE‐YOUNG LIM, Su-Hyun Gu, Byeong‐Teck Kang, Dae Young Kim, Dong‐Pyo Jang, EUNG‐JE WOO, Dae Young Kim, Zang‐Hee Cho, Hee‐Myung Park,

Herpesvirus Infections and Treatments

A Yorkshire terrier and a Chihuahua were referred for acute onset, generalized tonic‐clonic seizures and were suspected to have meningoencephalitis based on magnetic resonance (MR) imaging findings. Brain lesions appeared hyperintense with T2‐weighted imaging and hypointense with T1‐weighted imaging, and were characteristic of necrotizing meningoencephalitis. Both dogs were diagnosed with necrotizing meningoencephalitis based on pathologic findings. Fluorine‐18 fluorodeoxyglucose positron emission tomography (FDG‐PET) was performed on both animals before euthanasia with the permission of the owner. In FDG‐PET images, these lesions seen in MR images were characterized by multifocal or diffuse hypometabolism. Our FDG‐PET results provided evidence of glucose hypometabolism in areas of necrosis and cavitation associated with necrotizing meningoencephalitis. FDG‐PET has the potential to provide valuable diagnostic information in dogs with suspected necrotizing encephalitis.