Chromosomal changes in renal cell carcinoma
1990; Elsevier BV; Volume: 45; Issue: 2 Linguagem: Inglês
10.1016/0165-4608(90)90083-m
ISSN1873-4456
AutoresJean Raymond Teyssier, Daniel Ferre,
Tópico(s)Epigenetics and DNA Methylation
ResumoA cytogenetic study was performed in 18 renal cell carcinomas using a culture method previously described. The significance of chromosome involvement in clonal aberrations was evaluated according to the mean + 1 SD objective criterion. Chromosomes 3, 7, 9, and 17 were preferentially involved in both numerical and structural changes. The cytogenetic data have been correlated with the clinical staging, but in contrast to a previous study [11], abnormalities of chromosome 3 were not associated with a higher clinical stage.
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