Portal de Periódicos da CAPES

Voltage‐sensing phosphatase: actions and potentials

2008; Wiley; Volume: 587; Issue: 3 Linguagem: Inglês

10.1113/jphysiol.2008.163097

1469-7793

Yasushi Okamura, Yoshimichi Murata, Hirohide Iwasaki,

Neuroscience and Neural Engineering

Voltage sensors have been well studied in voltage-gated ion channels for neuronal excitation and muscle contraction. The recent discovery of a voltage-sensing phosphatase, VSP, has changed the idea that voltage sensors are unique to ion flux through membranes. Recent findings on mechanisms and potential applications of VSP are reviewed.