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Latent and lytic cycle promoters of Epstein-Barr virus.

1983; Springer Nature; Volume: 2; Issue: 8 Linguagem: Inglês

10.1002/j.1460-2075.1983.tb01588.x

1460-2075

Paul J. Farrell, Alan T. Bankier, Carl Séguin, Prescott L. Deininger, B. G. Barrell,

Eosinophilic Disorders and Syndromes

Research Article1 August 1983free access Latent and lytic cycle promoters of Epstein-Barr virus. P.J. Farrell P.J. Farrell Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author A. Bankier A. Bankier Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author C. Séguin C. Séguin Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author P. Deininger P. Deininger Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author B.G. Barrell B.G. Barrell Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author P.J. Farrell P.J. Farrell Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author A. Bankier A. Bankier Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author C. Séguin C. Séguin Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author P. Deininger P. Deininger Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author B.G. Barrell B.G. Barrell Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. Search for more papers by this author Author Information P.J. Farrell1, A. Bankier1, C. Séguin1, P. Deininger1 and B.G. Barrell1 1Laboratory of Molecular Biology, Medical Research Council Centre, Cambridge, UK. The EMBO Journal (1983)2:1331-1338https://doi.org/10.1002/j.1460-2075.1983.tb01588.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info Four RNA polymerase II promoters have been mapped in the DNA sequence of the EcoRI-H and -Dhet fragments of B95-8 Epstein-Barr virus. RNAs transcribed from three of these promoters are dramatically induced by treatment of B95-8 cells with 12-O-tetradecanoylphorbol-13-acetate (TPA). The other promoter is active with or without TPA treatment of the cells and is thus active in the latent virus cycle. Deletion mapping suggests that DNA sequence homologies between some of the promoters lie in the same region as essential upstream promoter elements. Previous ArticleNext Article Volume 2Issue 81 August 1983In this issue RelatedDetailsLoading ...