Selective biopsy of human Peyer's patches during ileal endoscopy
1987; Elsevier BV; Volume: 93; Issue: 6 Linguagem: Inglês
10.1016/0016-5085(87)90266-6
ISSN1528-0012
AutoresThomas T. MacDonald, Jo Spencer, Joanne L. Viney, Christopher B. Williams, J A Walker‐Smith,
Tópico(s)Immune Cell Function and Interaction
Resumochildren for suspected chronic inflammatory bowel disease, it is possible to visualize lymphoid follicles (Peyer's patches) in the last few centimeters of the terminal ileum.Biopsy specimens have been taken from these Peyer's patches and the lymphoid cells have been isolated by collagenase digestion.The mean cell yield of Peyer's patch ceils was 1.7 x 10' lymphocytes/g tissue.Isolated Peyer's patch cells were 26%--54% CD3+ (pan T cells), 14%-34%
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