Artigo Acesso aberto Revisado por pares

Nevus Ota and Nevus Ito in American Negroes**From the Departments of Dermatology, Wayne State University College of Medicine and Detroit Receiving Hospital (Hermann Pinkus, M.D., Chairman) Detroit, Michigan.Supported in part by research grant RG-4435 and C-2072 from the National Institutes of Health, U. S. Public Health Service, and in part by research contract DA-49-007-MD-584 from the Research and Development Division, Office of the Suregon General, Department of the Army.

1961; Elsevier BV; Volume: 36; Issue: 2 Linguagem: Inglês

10.1038/jid.1961.22

ISSN

1523-1747

Autores

Yutaka Mishima, B. Mevorah,

Tópico(s)

melanin and skin pigmentation

Resumo

Nevus fusco-caeruleus ophthalmo-maxillaris Ota is a congenital pigmentary disorder of the skin and mucous membranes, observed frequently in the yellow race. In 1938 (1) and 1939 (2), this condition was first reported by Ota at a dermatological society meeting in Japan. The following year, Ota's pupil Tanino (3), published a detailed description of 26 cases. According to this description, the pigmentation was usually unilateral, being most pronounced on the eye-lids and fading away towards the zygomatic and maxillary regions. These areas are innervated by the first and second branches of the trigeminal nerve. The lesions were composed of brown and blue macules the size of which varied from that of a grain of rice to that of a lentil. The overall pigment picture varied from deep purplish-blue to light brownish-blue. In 17 of these cases, there was an associated melanosis oculi, and in 3 cases the condition was bilateral.

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