Cefotaxime and desacetyl cefotaxime in human bile
1983; Springer Science+Business Media; Volume: 11; Issue: 2 Linguagem: Inglês
10.1007/bf01641077
ISSN1439-0973
AutoresFrieder Kees, Egid Strehl, Peter Dominiak, H. Grobecker, K. Seeger, G. Seidel, Barbara Neuhaus, L Sáfrány,
Tópico(s)Antibiotics Pharmacokinetics and Efficacy
ResumoTen patients were injected with 2 g cefotaxime i. v. The antibacterial activity in the bile was measured by the agar diffusion test and the concentrations of cefotaxime and desacetyl cefotaxime were determined by high performance liquid chromatography. The values found allow the use of cefotaxime in infectious biliary diseases.
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