Self-injurious behavior: a review of the behavior and biology of self- mutilation
1991; American Psychiatric Association; Volume: 148; Issue: 3 Linguagem: Inglês
10.1176/ajp.148.3.306
ISSN1535-7228
Autores Tópico(s)Ion channel regulation and function
ResumoBack to table of contents Previous article Next article No AccessSelf-injurious behavior: a review of the behavior and biology of self- mutilationPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.148.3.306AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractOBJECTIVE: The authors describe the clinical characteristics of self- injurious behavior, giving special emphasis to self-injurious behavior occurring among individuals with character disorders. DATA COLLECTION: They review data suggesting the involvement of serotonergic, dopaminergic, and opiate neurotransmitter systems in the expression of self-injurious behavior. FINDINGS: Self-injurious behavior occurs among mentally retarded individuals, psychotic patients, prison populations, and individuals with severe character disorders. Although theoretical psychological models of self-injurious behavior are helpful in understanding the patient's experience of self-injury, no generally useful therapeutic approach has yet evolved from these models. Data derived from animal models and treatment studies suggest the involvement of opiatergic and dopaminergic mechanisms in self-injury among the mentally retarded. Serotonergic influences on self-injurious behavior may be present in varying forms of this behavior. The scientific literature on the benefits of pharmacological agents for mentally retarded individuals is beset with a number of problems. Support is emerging, however, for the use of lithium and carbamazepine with self-injuring mentally retarded patients, and some behavioral interventions appear to be successful for mentally retarded individuals. Self-injuring patients with borderline personality disorder may benefit from milieu treatment. CONCLUSIONS: Although no form of treatment has yet been demonstrated to be of general benefit, the literature suggests that therapeutic trials with dopamine antagonists, serotonin reuptake inhibitors, and opiate antagonists may be of value. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byGenital Mutilation in Males19 November 2022 | Current Urology Reports, Vol. 24, No. 3Psychopathological and Neurobiological Overlap Between Anorexia Nervosa and Self-Injurious Behavior: A Narrative Review and Conceptual Hypotheses11 May 2022 | Frontiers in Psychiatry, Vol. 13Behandlung dissoziativer Symptome mit Nalmefen bei Patienten mit Borderline-Persönlichkeitsstörung und komplexer posttraumatischer Belastungsstörung3 December 2021 | Der Nervenarzt, Vol. 93, No. 5"I'm getting too old for this stuff": The conceptual structure of tattoo aestheticsActa Psychologica, Vol. 219Stop touching your face! 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KALICHMAN1 April 2006 | American Journal of Psychiatry, Vol. 148, No. 11Laws on reporting sexual abuse of children23 January 2015 | American Journal of Psychiatry, Vol. 148, No. 11Dr. Westen and Dr. Ludolph ReplyDREW WESTEN, and PAMELA LUDOLPH1 April 2006 | American Journal of Psychiatry, Vol. 148, No. 10Dr. Weissman and Associates ReplyMYRNA M. WEISSMAN, JEFFREY P. KAHN, JEFFREY MARKOWITZ, ROBERT OUELLETTE, and STEVEN GREENWALD1 April 2006 | American Journal of Psychiatry, Vol. 148, No. 10Opiate System in Self-Injurious BehaviorSTEPHEN J. CHERNAIK1 April 2006 | American Journal of Psychiatry, Vol. 148, No. 10Dr. Winchel and Dr. Stanley ReplyRONALD M. WINCHEL, and MICHAEL STANLEY1 April 2006 | American Journal of Psychiatry, Vol. 148, No. 10Increased risk of stroke in patients with panic attacks: real or perceived?23 January 2015 | American Journal of Psychiatry, Vol. 148, No. 10Opiate system in self-injurious behavior23 January 2015 | American Journal of Psychiatry, Vol. 148, No. 10 Volume 148Issue 3 March 1991Pages 306-317 Metrics PDF download History Published online 1 April 2006 Published in print 1 March 1991
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