Portal de Periódicos da CAPES

Structure of Pummeloquinone, a New Coumarin-Naphthoquinone Dimer Isolated from Citrus Plants.

1993; Pharmaceutical Society of Japan; Volume: 41; Issue: 1 Linguagem: Inglês

10.1248/cpb.41.205

1347-5223

Chihiro Ito, Tomohisa Ono, Emiko Tanaka, Yuko Takemura, Toshimi NAKATA, Hiromi Uchida, Motoharu Ju‐ichi, Mitsuo Omura, Hiroshi Furukawa,

Phytochemical compounds biological activities

Pummeloquinone (1), the third example of a coumarin-naphthoquinone dimer from a natural source, was isolated form the roots of several hybrid seedlings resulting from a cross of May pummelo x Marsh grapefruit (Rutaceae) grown in an orchard at Okitsu, Shizuoka, and its structure was elucidated by chamical and spectrometric methods. Synthesis of 1 was also achieved by Diels-Alder reaction between trans-dehydroosthol (3) and 2-methoxy-1, 4-benzoquinone followed by 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone (DDQ) oxidation.