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Simple Behavioral Assessment of Mouse Olfaction

2009; Wiley; Volume: 48; Issue: 1 Linguagem: Inglês

10.1002/0471142301.ns0824s48

1934-8584

Mu Yang, Jacqueline N. Crawley,

Neurobiology and Insect Physiology Research

Abstract This unit presents two basic protocols that offer rapid assessments of anosmia (the absence of a sense of smell) in mice. The buried food test is used to check for the ability to smell volatile odors. The olfactory habituation/dishabituation test is used to test whether the animal can detect and differentiate different odors, including both nonsocial and social odors. A non‐contact method of odor presentation, along with a general method for collecting urine samples, is given as an alternate protocol. The tests described in this unit only require simple equipment and can be adopted readily by most laboratories. Curr. Protoc. Neurosci . 48:8.24.1‐8.24.12. © 2009 by John Wiley & Sons, Inc.