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SPLENECTOMY IN RHEUMATOID ARTHRITIS

1953; American College of Physicians; Volume: 38; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-38-4-787

1539-3704

Charles LeRoy Steinberg,

Rheumatoid Arthritis Research and Therapies

Article1 April 1953SPLENECTOMY IN RHEUMATOID ARTHRITISCHARLES LEROY STEINBERG, B.S., M.D., F.A.C.P.CHARLES LEROY STEINBERG, B.S., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-38-4-787 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this paper is to suggest a new cause and effect for the beneficial sequelae produced by splenectomy in Felty's syndrome. Felty1 described a syndrome of mild rheumatoid arthritis associated with fever, secondary anemia (in four of five cases reported), leukopenia ranging from 1,000 to 4,200 leukocytes, splenomegaly and tachycardia. Rheumatologists are practically unanimous in believing that this syndrome is a variant of rheumatoid arthritis.Forty-six papers1-46have been published on the value of splenectomy in rheumatoid arthritis; 37 patients have been described in these papers as having undergone splenectomy successfully. The effects of splenectomy in these cases...Bibliography1. Felty AR: Chronic arthritis in the adult, associated with splenomegaly and leucopenia, Bull. Johns Hopkins Hosp. 35: 16, 1924. Google Scholar2. HanrahanMiller EMSR: Effect of splenectomy in Felty's syndrome, J. A. M. A. 99: 1947, 1932. Google Scholar3. Craven EB: Splenectomy in chronic arthritis, associated with splenomegaly and leucopenia (Felty's syndrome), J. A. M. A. 102: 823, 1934. CrossrefGoogle Scholar4. Alessandrini P: Felty's syndrome, Minerva med. 1: 310, 1934. Google Scholar5. Fritz R: Painful joints, splenomegaly and anemia, M. Clin. North America 18: 1053-1066, 1935. Google Scholar6. 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Author, Article, and Disclosure InformationAffiliations: Rochester, N. Y.*Received for publication October 11, 1952. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe spleen in Felty's syndrome: A histological, morphometrical, and immunohistochemical studyThe rarity of felty's syndrome in blacksSplenectomy for hematologic disordersClinical and Serologic Observations on 27 Patients with Felty's SyndromeHematologic disorder in Felty's syndromeThe variable features of Felty's syndromeIndikationen zur Splenektomie bei BlutkrankheitenFELTY'S SYNDROMERHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (ELEVENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.The Anemia of Rheumatoid Arthritis 1 April 1953Volume 38, Issue 4Page: 787-813KeywordsAnemiaFelty syndromeFeversPhotographyRheumatoid arthritisSplenectomySplenomegalyTachycardia ePublished: 1 December 2008 Issue Published: 1 April 1953 PDF downloadLoading ...