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Artigo Revisado por pares
BIBTEX RIS

DNA recognition by the helix-turn-helix motif

1992; Elsevier BV; Volume: 2; Issue: 1 Linguagem: Inglês

10.1016/0959-440x(92)90184-9

ISSN

1879-033X

Autores

Richard G. Brennan,

Tópico(s)

DNA and Nucleic Acid Chemistry

Resumo

Highlights of the past year's studies on helix-turn-helix proteins include the striking details of DNA bending by Escherichia coli catabolite gene activator protein, the structure determination of the E. coli factor for inversion stimulation, and the continued elucidation of specific protein-DNA interactions. In addition, the importance of residues outside the helix-turn-helix motif and of protein conformational changes to DNA binding specificity were underscored.

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