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Caracterização do aneurisma apical da cardiopatia chagásica crônica mediante uso de corregistro de imagens cintilográficas

2007; Sociedade Brasileira de Cardiologia (SBC); Volume: 89; Issue: 2 Linguagem: Inglês

10.1590/s0066-782x2007001400010

1678-4170

Marcus Vinı́cius Simões, Lucas Ferrari de Oliveira, Flávio C. Hiss, Alexandre Baldini de Figueiredo, Antônio Osvaldo Pintya, Benedito Carlos Maciel, José Antônio Marin‐Neto,

Malaria Research and Control

.Recent clinical trials have shown that the presence of this cardiac lesion is an independent risk factor for cardioembolic stroke in patients with chronic Chagas’ heart disease 3-5 . Therefore, early detection of the aneurysm using several diagnostic imaging methods is clinically relevant because of its therapeutic implications. ECG-gated SPECT myocardial perfusion imaging has been recently validated for assessing left ventricular function, and is now widely used 6 . Visual analysis of tomographic slices displayed in cine mode allows the identification of dyskinetic areas, including left ventricle aneurysms, associated with ischemic heart disease 7 . Nevertheless, while many Chagasic patients undergo myocardial perfusion imaging due to symptoms suggestive of myocardial ischemia, there is no report on characterization of the apical aneurysm of chronic Chagas’ disease by gated-SPECT. Multi-gated blood pool SPECT (MUGA-SPECT), which produces images of the ventricular cavity, and gated-SPECT (which produces images of the ventricular walls) provide complementary information for better characterization of this form of ventricular lesion in chronic Chagas’ heart disease. Recent computational techniques allow these images to be aligned and co-registered, with simultaneous visualization of these structures. This report describes the anatomical and functional characteristics of apical aneurysms in chronic Chagas’ heart disease patients using different modalities of three-dimensional cardiac image co-registration, most specifically, myocardial perfusion and labeled blood pool images.