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The prevalence, risks, and management of Chlamydia trachomatis infections in fertile and infertile patients from the high socioeconomic bracket of the South African population

1991; Elsevier BV; Volume: 56; Issue: 3 Linguagem: Inglês

10.1016/s0015-0282(16)54545-2

1556-5653

P Wessels, Gerrit J. Viljoen, Nico Francois Marais, Johan Albert Anthonie de Beer, Frank M. Smith, A Gericke,

Urinary Tract Infections Management

The main objective of the study was to evaluate the prevalence of Chlamydia trachomatis endocervicitis in an infertile population. Forty consecutive patients were enrolled in the study group and 41 in the control group. The study was undertaken in the Department of Obstetrics and Gynaecology of the University of the Orange Free State, Bloemfontein, Republic of South Africa. Infertile white females, visiting an infertility clinic in an academic hospital and fertile white female patients visiting an antenatal clinic. Endocervical swabs were taken, and monoclonal direct immunofluorescence for C. Trachomatis were done on each. A difference was expected between the prevalence of C. trachomatis infection in the fertile and infertile population. In the study group, 14(35.9%) positive, 25(64.1%) negative, and 1 fallout were obtained. In the control group, 3 patients (7.32%) tested positive. Although no correlation was found between C. trachomatis infection of the female genital tract and the clinical history, it showed a significant correlation with infertility. This justifies routine screening tests and antibiotic treatment of positive infertile couples. Analysis of cost-effectiveness showed that empirical treatment of new infertile couples is justified in some populations.