Alterations in the Nuclear Architecture Produced by the Overexpression of Tau Protein in Neuroblastoma Cells
2013; IOS Press; Volume: 36; Issue: 3 Linguagem: Inglês
10.3233/jad-122401
ISSN1875-8908
AutoresHugo Christian Monroy-Ramírez, Gustavo Basurto‐Islas, Raúl Mena, Bulmaro Cisneros, Lester I. Binder, Jesús Ávila, Francisco García‐Sierra,
Tópico(s)Microtubule and mitosis dynamics
ResumoAbnormal intracellular aggregation of tau protein is a pathological condition leading to neuronal death in Alzheimer's disease. Fibrillar and nonfibrillar aggregates of tau protein alter the normal functioning of neurons by disturbing important cellu
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