Artigo Revisado por pares

Alterations in the Nuclear Architecture Produced by the Overexpression of Tau Protein in Neuroblastoma Cells

2013; IOS Press; Volume: 36; Issue: 3 Linguagem: Inglês

10.3233/jad-122401

ISSN

1875-8908

Autores

Hugo Christian Monroy-Ramírez, Gustavo Basurto‐Islas, Raúl Mena, Bulmaro Cisneros, Lester I. Binder, Jesús Ávila, Francisco García‐Sierra,

Tópico(s)

Microtubule and mitosis dynamics

Resumo

Abnormal intracellular aggregation of tau protein is a pathological condition leading to neuronal death in Alzheimer's disease. Fibrillar and nonfibrillar aggregates of tau protein alter the normal functioning of neurons by disturbing important cellu

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