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Small t protein of simian virus 40 is required for dense focus formation in a rat cell line

1982; American Society for Microbiology; Volume: 41; Issue: 3 Linguagem: Inglês

10.1128/jvi.41.3.1073-1075.1982

1098-5514

Sumio Sugano, Nobuo Yamaguchi, H Shimojo,

Animal Virus Infections Studies

Incomplete foci were formed in a Fischer rat cell line infected with simian virus 40 detection mutants encoding defective small t antigen. The foci were small and rarely piled up. The fraction of DNA-synthesizing cells in the foci was about half of that induced by wild-type virus.