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BIBTEX RIS

Characterization of Gazdar murine sarcoma virus by nucleic acid hybridization and analysis of viral expression in cells

1977; American Society for Microbiology; Volume: 24; Issue: 2 Linguagem: Inglês

10.1128/jvi.24.2.551-556.1977

ISSN

1098-5514

Autores

R H Pang, Leo A. Phillips, D. K. Haapala,

Tópico(s)

Animal Virus Infections Studies

Resumo

Gazdar murine sarcoma virus (Gz-MSV) and Moloney murine sarcoma virus (M-MSV) are closely related. The complete M-MSV-specific nucleic acid sequences constituted a major portion of Gz-MSV-specific sequences. The MSV-specific sequences in both Gz-MSV and M-MSV genomes shared homology with hamster leukemia virus nucleic acid sequences. Both rat cells (S+L+) and hamster (S+L-) cells expressed two viral proteins of 68,000 and 70,000 daltons. These proteins were immunologically related to p60 purified from m1 virions of M-MSV.

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