Computational Options for Bioinformatics Research in Evolutionary Biology
2005; Springer Science+Business Media; Linguagem: Inglês
10.1007/11428848_9
ISSN1611-3349
AutoresMichael A. Thomas, Mitch D. Day, Luobin Yang,
Tópico(s)Evolution and Genetic Dynamics
ResumoThis review will introduce areas of evolutionary research that require substantial computing resources using the examples of phylogenetic reconstruction and homology searching. We will discuss the commonly used analytical approaches and computational tools. We will discuss two computing environments employed by academic evolutionary researchers. We present a simple empirical demonstration of scalable cluster computing using the Apple Xserve solution for phylogenetic reconstruction and homology searching. We conclude with comments about tool development for evolutionary biology and Open Source strategies to promote scientific inquiry.
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