Fragmented QRS Complexes Are Associated with Cardiac Fibrosis and Significant Intraventricular Systolic Dyssynchrony in Nonischemic Dilated Cardiomyopathy Patients with a Narrow QRS Interval
2010; Wiley; Volume: 28; Issue: 1 Linguagem: Inglês
10.1111/j.1540-8175.2010.01242.x
ISSN1540-8175
AutoresYelda Başaran, Kürşat Tigen, Tansu Karaahmet, I Işıklar, Cihan Çevik, Emre Gürel, Cihan Dündar, Selçuk Pala, Kamran Mahmutyazıcıoğlu, Özcan Başaran,
Tópico(s)Cardiomyopathy and Myosin Studies
ResumoEchocardiographyVolume 28, Issue 1 p. 62-68 Fragmented QRS Complexes Are Associated with Cardiac Fibrosis and Significant Intraventricular Systolic Dyssynchrony in Nonischemic Dilated Cardiomyopathy Patients with a Narrow QRS Interval Yelda Basaran M.D., Yelda Basaran M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorKursat Tigen M.D., Kursat Tigen M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorTansu Karaahmet M.D., Tansu Karaahmet M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorIclal Isiklar M.D., Iclal Isiklar M.D. Department of Radiology, Baskent University School of Medicine, Istanbul, TurkeySearch for more papers by this authorCihan Cevik M.D., Cihan Cevik M.D. Texas Heart Institute St. Luke's Episcopal Hospital, Cardiology Division, Houston, TexasSearch for more papers by this authorEmre Gurel M.D., Emre Gurel M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorCihan Dundar M.D., Cihan Dundar M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorSelcuk Pala M.D., Selcuk Pala M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorKamran Mahmutyazicioglu M.D., Kamran Mahmutyazicioglu M.D. Sema Hospital Department of Radiology, Istanbul, TurkeySearch for more papers by this authorOzcan Basaran M.D., Ozcan Basaran M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this author Yelda Basaran M.D., Yelda Basaran M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorKursat Tigen M.D., Kursat Tigen M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorTansu Karaahmet M.D., Tansu Karaahmet M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorIclal Isiklar M.D., Iclal Isiklar M.D. Department of Radiology, Baskent University School of Medicine, Istanbul, TurkeySearch for more papers by this authorCihan Cevik M.D., Cihan Cevik M.D. Texas Heart Institute St. Luke's Episcopal Hospital, Cardiology Division, Houston, TexasSearch for more papers by this authorEmre Gurel M.D., Emre Gurel M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorCihan Dundar M.D., Cihan Dundar M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorSelcuk Pala M.D., Selcuk Pala M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this authorKamran Mahmutyazicioglu M.D., Kamran Mahmutyazicioglu M.D. Sema Hospital Department of Radiology, Istanbul, TurkeySearch for more papers by this authorOzcan Basaran M.D., Ozcan Basaran M.D. Cardiology Department, Kartal Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeySearch for more papers by this author First published: 23 January 2011 https://doi.org/10.1111/j.1540-8175.2010.01242.xCitations: 81 Address for correspondence and reprint requests: Kursat Tigen, M.D., Kartal Kosuyolu Kalp Egt. ve Arst. Hastanesi, Denizer Cad. Cevizli, Kartal, Istanbul, Turkey. Fax: +90 216 459 63 21; E-mail: [email protected] Disclosures: None. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Background: Myocardial scar causes heterogeneous ventricular activation, which results in fragmentation of QRS complexes on ECG. Myocardial fibrosis in patients with nonischemic cardiomyopathy (NDCM) can be identified as late gadolinium enhancement (LGE) areas on cardiac magnetic resonance (CMR) studies. We investigated the association of fragmented QRS (fQRS) complexes with systolic dyssynchrony and myocardial fibrosis in patients with NDCM. Methods: Twenty patients with NDCM and sinus rhythm who had fQRS complexes were evaluated with CMR. The association of fQRS complexes with LGE and systolic dyssynchrony was investigated. Results: Nineteen patients had significant systolic dyssynchrony with echocardiography. Among 19 patients with significant dyssynchrony, 14 (74%) patients had fQRS complexes in the most delayed contracting segment or one of the dyssynchronous segments, whereas five patients (26%) had fQRS complexes in a lead which is discordant with the dyssynchronous segment on echocardiography. Seventeen patients had LGE in their CMR. Among the 17 patients with LGE; 13 patients (76%) had fQRS complexes concordant with LGE present segments. Conclusion: Fragmentation of QRS complexes on ECG is associated with intraventricular systolic dyssynchrony and subendocardial fibrosis in NDCM patients with a narrow QRS interval and sinus rhythm. (Echocardiography 2011;28:62-68) Citing Literature Volume28, Issue1January 2011Pages 62-68 RelatedInformation
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