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The role of growth in endocrine regulation of salmon smoltification

1997; Springer Science+Business Media; Volume: 17; Issue: 1/6 Linguagem: Inglês

10.1023/a

1573-5168

Walton W. Dickhoff, Brian R. Beckman, Donald A. Larsen, C. Duan, Shunsuke Moriyama,

Aquaculture Nutrition and Growth

Keywords: growth, salmon, smoltification, insulin, insulin-like growth factor I (IGF-I), growthhormone, thyroxine, photoperiod, temperature, nutritioncreases hepatic IGF-I mRNA (Cao et al. 1989;Sakamoto and Hirano 1993; Duan et al. 1994) andelevates blood IGF-I levels (Moriyama et al.1994). The majority of IGF-I in salmonid blood isprobably bound to specific binding proteins(IGFBPs), some of which are influenced by GH,insulin and nutrition (Kelley et al. 1992; Siharathand Bern 1993). The IGFBPs in blood and in tis-sues surrounding target cells undoubtedly play asignificant role in modifying the action of IGF-Iin fish, as they do in mammals, although this islargely unexplored in the context of salmon smol-tification. IGF-I inhibits GH release by negativefeedback, as shown