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Orbital exenterations: an 18-year experience from a single head and neck unit

2010; Wiley; Volume: 81; Issue: 5 Linguagem: Inglês

10.1111/j.1445-2197.2010.05592.x

1445-2197

Chih-Hung Kuo, Kan Gao, Anthony Clifford, Kerwin F. Shannon, Jonathan R. Clark,

Oral and Maxillofacial Pathology

ANZ Journal of SurgeryVolume 81, Issue 5 p. 326-330 Orbital exenterations: an 18-year experience from a single head and neck unit Chih-Hung Kuo, Corresponding Author Chih-Hung Kuo Central Clinical School, Sydney Medical School, and Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaDr Chih-Hung Kuo, Central Clinical School, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW 2050, Australia. Email: [email protected]Search for more papers by this authorKan Gao, Kan Gao Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this authorAnthony Clifford, Anthony Clifford Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this authorKerwin Shannon, Kerwin Shannon Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this authorJonathan Clark, Jonathan Clark Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this author Chih-Hung Kuo, Corresponding Author Chih-Hung Kuo Central Clinical School, Sydney Medical School, and Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaDr Chih-Hung Kuo, Central Clinical School, Royal Prince Alfred Hospital, Camperdown, Sydney, NSW 2050, Australia. Email: [email protected]Search for more papers by this authorKan Gao, Kan Gao Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this authorAnthony Clifford, Anthony Clifford Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this authorKerwin Shannon, Kerwin Shannon Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this authorJonathan Clark, Jonathan Clark Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, Royal Prince Alfred Hospital, Sydney, AustraliaSearch for more papers by this author First published: 23 December 2010 https://doi.org/10.1111/j.1445-2197.2010.05592.xCitations: 34 C.-H. Kuo MB BS, BSc(Med); K. Gao B Eng; A. Clifford MB BS, FRACS; K. Shannon MB BS, FRACS; J. Clark MB BS (Hons), BSc, FRACS. The corresponding author is not a recipient of a research scholarship. The preliminary results of this paper were presented at the 41st annual scientific congress of the Royal Australian and New Zealand College of Ophthalmologists in Brisbane, 2009. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract Background: To review the outcomes of the patients who undergo orbital exenteration for malignancy. Methods: A retrospective review of patients who underwent orbital exenteration performed at Royal Prince Alfred and Concord Hospitals between 1990 and 2008. Results: A total of 38 patients were identified. The most common malignancies were squamous cell carcinoma (14 cutaneous and five mucosal origin), basal cell carcinoma (12 cutaneous) and melanoma (five patients). Orbital invasion was the main indication for orbital exenteration. Additional procedures were performed in 29 (76%) patients at the time of exenteration, including craniotomies in eight patients and maxillectomy in 15 patients. Flap reconstructions were required in 35 (92%) patients, including 33 free flap repairs and two local flap repairs. Post-operative complications included cerebrospinal fluid leak (16%) and wound-related complications (13%). The disease-specific survival rate was 97% at 1 year and 92% at 5 years. The local control rate was 83% at 1 year and 55% at 5 years. Fifty per cent of patient mortality and 63% of local recurrence occurred within the first post-operative year. Conclusions: In this series, locoregional control and survival were high, suggesting that aggressive surgical measures such as orbital exenteration are not unreasonable in well-selected patients. Free flap reconstruction is a reliable reconstructive technique which may reduce major complications. The first post-operative year is the most important period when monitoring for recurrence. Citing Literature Volume81, Issue5May 2011Pages 326-330 RelatedInformation