Portal de Periódicos da CAPES

Efeito da Gymnema sylvestre na elevação da lipidemia após administração de gordura de origem animal em ratos wistar

2004; Editora da Universidade Estadual de Maringá (Eduem); Volume: 26; Issue: 3 Linguagem: Inglês

10.4025/actascibiolsci.v26i3.1602

1807-863X

Márcia Regina Batista, Elizete Rosa dos Santos Silva, Roberto Barbosa Bazotte, Marcio dos Santos Vasconcelos,

Food Science and Nutritional Studies

The aim of the present experiment was to investigate the influence of Gymnema sylvestre (Gs) on the elevation of blood levels of lipids after administration of animal fat in male Wistar rats (230–250g). The animals, which were fasted for 22h, were separated in five groups that received (8:00 a.m) intragastric administration of: 1) 2ml of pork fat Batavo® /kg of body weight (PFB); 2) PFB+500mg/kg of Gs body weight (Gs 500mg); 3) PFB + 1g/kg of Gs body weight (Gs 1 g); 4) Gs 500mg; 5) Gs 1g. The animals were sacrificed 30min after the administration of these substances. No significant differences were verified in the serum concentration of total lipids, triglycerides and cholesterol in the animals, which received PBF in the presence or absence of Gs 500mg or Gs 1g. Therefore, the results showed that Gs could not affect the intestinal absorption of lipids