Artigo Acesso aberto Produção Nacional Revisado por pares

Flavonóides de Cissus verticillata e a atividade hipoglicemiante do chá de suas folhas

2002; Springer Science+Business Media; Volume: 12; Linguagem: Inglês

10.1590/s0102-695x2002000300007

ISSN

1981-528X

Autores

Wagner Luiz Ramos Barbosa, Wallace Raimundo A dos Santos, Lucianna N. Pinto, Isabel C.C. Tavares,

Tópico(s)

Natural Antidiabetic Agents Studies

Resumo

Cissus verticillata, a Vitaceae very used in the traditional medicine in Pará and Minas Gerais State -Brazil, was investigated in order to validate its indication for the hyperglycaemia control.The aqueous extract reduces the normal glycaemia of male white Wistar rats in about 19.5 %.The hypoglycaemic effect of this extract could be related to the flavonoids found in the preparation.Luteolin, Kaempferol and Luteolin-3'-sulphate could be isolated from the aqueous extract after acid hydrolysis.

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