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BIBTEX RIS

Arrabidaea chica (HBK) Verlot: phytochemical approach, antifungal and trypanocidal activities

2008; Springer Science+Business Media; Volume: 18; Issue: 4 Linguagem: Inglês

10.1590/s0102-695x2008000400008

ISSN

1981-528X

Autores

Wagner Luiz Ramos Barbosa, Lucianna do Nascimento Pinto, Etienne Louis Jacques Quignard, José Maria dos Santos Vieira, José Otávio Carréra Silva Júnior, Sérgio de Albuquerque,

Tópico(s)

Phytochemicals and Antioxidant Activities

Resumo

Arrabidaea chica (HBK.) Verlot (Bignoniaceae) vernacular name "Pariri", is a climbing shrub, widespread from South Mexico to Guyana and central Brazil and is traditionally indicated to treat symptoms of inflammations and skin affections. Its ethanol extract was chemically investigated and tested against yeasts and dermatophytic fungi. The trypanocidal activity of the same extract was also evaluated. This work reports the isolation of three flavonoids, the total growth inhibition of Trichophyton mentagrophytes and a significant trypanocidal effect of the ethanol extract and its fractions. No relevant acute toxicity was detected even at a dose of 1000 mg/kg.

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