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Patent Ductus Arteriosus: Clinical Relevance of Prostaglandins and Prostaglandin Inhibitors in PDA Pathophysiology and Treatment

1995; Elsevier BV; Volume: 22; Issue: 2 Linguagem: Inglês

10.1016/s0095-5108(18)30293-8

1557-9840

Cathy Hammerman,

Transplantation: Methods and Outcomes

This article presents a comprehensive review of the patent ductus arteriosus which so often affects the premature neonate. Included are a discussion of the unique anatomy and physiology of the ductus, a review of the mechanisms involved in normal closure, and factors leading to persistent patency. Various therapeutic options also are discussed, including some new and innovative approaches.